Vincent Marcucci
Gallstone Ileus (GI) is an uncommon pathology generally affecting elderly females with a history of untreated cholelithiasis. The development of GI is a sequel from a fistulous connection resulting from a chronic inflammatory state between the gallbladder and intestinal tract; most commonly the second (descending) segment of the duodenum. However, individuals suffering from a neurodegenerative disorder, such as Amyotrophic Lateral Sclerosis (ALS) causing autonomic dysfunction with resultant gut dysmotility and predisposition to gallstone formation may be at a significantly higher risk of morbidity in this patient population in regards to the development of GI.