Cholecalciferol for Primary Dysmenorrhea in a College- aged | 3392

Журнал биологии и современного мира

ISSN - 2322-3308


Cholecalciferol for Primary Dysmenorrhea in a College- aged Population- A Clinical Trial

Mina Ataee, Maryam Zangeneh, Mohammad Mahboubi

"Primary dysmenorrhea is the most common gynecological complaints among adolescents. The purpose of the present study is to evaluate the effect of vitamin-D in reduction of pelvic pain in women suffering primary dys-menorrhea. This double blind randomized clinical trial was performed on women suffering from primary dys-menorrhea. For case group (n=27), vitamin-D was prescribed as a single dose of 300 000IU starting 5 days be-fore the beginning of menstruation, for three consecutive cycles. For control group (n=27), a Placebo was pre-scribed. Pain severity was evaluated using Visual Analogue Scale (VAS). There was a reduction of the pain score in the first month for both groups (mean score of 5.3±2.24 for group-A and 5.21±2.35 for group-B). In the next two months pain reduction continued for group-A, but for group-B pain scores grows higher than the first month. In-dependent student t-test showed that pain score was significantly lower in group-A than group-B after beginning of therapy in the second and third month (P= 0.023 and 0.001 respectively).There was no significant difference between two groups in the level of vitamin-D in follicular and luteal Phase. Vitamin-D causes significant pain re-duction in primary dysmenorrhea that due to its safety can be a simple treatment for this problem."